Ophthalmic Preparations: Principles of Ocular Pharmacology
This webinar is part one of three in the webinar series on ophthalmic preparations. Part I, Principles of Ocular Pharmacology, reviews the basic principles of ocular pharmacology, including anatomy and pharmacokinetics. Part II, Formulation Considerations, surveys the art and science of compounding by reviewing the guidelines for sterile compounding and for preparing ophthalmic formulations. Finally, Part III, Compounding Opportunities, applies what was learned by looking at specific examples of compounding opportunities in both human and veterinary ophthalmology.
The eye is a small organ, only about 23 mm in axial diameter, and yet it is a complex structure composed of many different tissues working together with the brain to provide us vision. A solid understanding of the ocular anatomy and physiology is necessary prior to studying its pharmacotherapy. Thus, in this module, we will go into a review of the basic organization of the eye, after which we will examine the many different routes of drug administration available to the healthcare provider and the barriers encountered in ocular pharmacotherapy.
When discussing pharmacokinetics, we readily think about absorption, distribution, metabolism, and elimination. The eye, however, is a dynamic organ with limited access; thus, little is known about the volumes of distribution across ocular tissues and drug metabolism. In this module, we will instead follow the path the drug takes once it is administered to the eye, and from here we will discuss the drug-specific and eye-specific factors that can affect drug pharmacokinetics.
- Pharmacy Technicians
- Nurse Practitioners
- Review the basic anatomy and physiology of the human eye
- Understand the different routes of ocular drug administration and the barriers that limit drug bioavailability in eye tissues
- Learn the pharmacokinetics of the most common routes of ocular drug administration
- Identify factors that can influence the drug pharmacokinetics
The webinar is copyright © 2018 LP3 Network.
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JADE MARIE LASISTE, MD, MSc
Jade Marie Lasiste completed her Masters of Science in Pathology, alongside a research fellowship in Ocular Pathology, at McGill University. Her work was focused on cataracts and uveal melanoma, for which she was the recipient and several national and international research awards. In addition she completed her Bachelor of Science in Molecular Biology and Biotechnology and her Doctor of Medicine at the University of the Philippines. She is currently a Junior Medical Writer at LP3 Network Inc.
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