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Hazardous Drug Decontamination – Understanding its Purpose and Validating Best Practices (PFM On-demand)


Compounders working with hazardous drugs (HD) face the daily challenge of surface contamination, as HD poses a threat of unintended exposure unless proper removal from work surfaces takes place. Despite practice and quality standards set out by USP Chapter <800>, confusion remains among the compounding community with HD removal, particularly decontamination.

This activity aims to clarify the purpose of decontamination of non-sterile and sterile preparations by exploring the differences between deactivation, decontamination, cleaning, and disinfection, as well as discussing appropriate agents for the decontamination of HD on surfaces. Under a practice setting, the program will also explore the importance of verifying processes and agents for decontaminating, while discussing procedures for validating effective HD decontamination.

Further recognizing the risks of HD exposure and the significance of decontamination can facilitate staff safety and policy compliance, thereby reducing residual surface contamination and hence risk of potentially life-threatening exposure.

Intended audience

    • Pharmacists & Pharmacy Technicians

    Learning Objectives


    1. Review the differences between deactivation, decontamination, cleaning, and disinfection.
    2. Discuss agents that are appropriate for the decontamination of hazardous drugs on surfaces.
    3. Explain the importance of verifying the effectiveness of your process and agents for decontaminating hazardous drugs.
    4. Describe options for verifying effective hazardous drug decontamination.

    Pharmacy Technicians

    1. Define decontamination in the context of hazardous drugs removal.
    2. List agents suitable for the decontamination of hazardous drugs on surfaces.
    3. Recognize the significance of validating the effectiveness of your procedure and the agents used for decontaminating hazardous drugs.
    4. Identify ways to facilitate the verification of effective hazardous drug decontamination.

    Hardware/software requirements

    Web browser

    Google Chrome (most recent 2 versions)

    Mozilla Firefox (most recent 2 versions)

    Internet Explorer v11

    Apple Safari (most recent 2 versions)

    Microsoft Edge (most recent 2 versions)

    Internet connection

    Computer: 1 Mbps or better (broadband recommended)

    Mobile device: 3G or better (WiFi recommended)


    No additional software needed


    2GB of RAM (minimum), 4GB or more of RAM (recommended)



    This webinar is Copyright © Alliance for Pharmacy Compounding 2022.

    Course summary
    Available credit: 
    • 0.10 CEU (ACPE)
    • 1.00 Contact Hours
    Abby Roth

    Abby Roth, founder of Pure Microbiology, has over 17 years of experience in supporting the testing and consulting needs of the pharmaceutical, medical device, and compounding industries. Her background in pharmaceutical microbiology includes extensive knowledge of environmental monitoring. Abby served as a USP Compounding EC member during the 2015-2020 cycle.

    Abby has been invited to speak for state Boards of Pharmacy and for organizations, such as the National Home Infusion Association (NHIA) and the American Society of Health-System Pharmacists (ASHP), on topics related to viable sampling, sterilization, sterile compounding, and hazardous drugs.


    This CE Activity is accredited for Pharmacists and Pharmacy Technicians by the Accreditation Council for Pharmacy Education (ACPE) through CPE Consultants, LLC.

    Total CPE Credits: 1 CPE Hour = 0.1 CEUs

    Credits1 CPE Hour = 0.1 CEUs
    Release DateAugust 18, 2022
    Expiration DateAugust 18, 2025


    1. View the recorded webinar in full.
    2. Pay the credit reporting fee of $10.00 USD.
    3. Complete a learning assessment (minimum 80% passing grade, two attempts permitted) within 60 days.
    4. Submit a completed live event evaluation form online within 60 days.

    When the aforementioned steps have been completed and approved:

    • Pharmacists and Pharmacy Technicians registered in the United States will obtain a statement of completed credits on their NABP e-Profile within 60 days.
    • Pharmacists and Pharmacy Technicians registered elsewhere will receive an automated email from LP3 Network advising that they can download a statement of participation.
    • All participants will receive an automated email from LP3 Network advising that they can download the LP3 Network certificate of completion.
    accreditorCPE Consultants, LLC is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

    International participants should verify with their respective governing board for accreditation equivalency.

    Please note: You can enroll in the course for free using the access code you were provided with, to get access to the slides and recording. The credit reporting fee of $10.00 USD only needs to be paid if you intend to claim credits. Upon payment, you will get access to the learning assessment and evaluation form, which must be completed to receive credits.


    There are no refunds, returns or transfers upon payment of the credit reporting fee.


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