This activity affords the student pharmacist the opportunity to complete master formulation records, while preparing compounded medications that incorporate manufactured delivery systems for oral liquids and topical creams. The student pharmacist will realize the importance of evaluating the appropriateness of delivery systems when compounding medications. Emphasis is on the management of the master formulation record, ensuring completeness of recordings, and consistency in performance. 



  • Prepare two compounded medications from established master formulation records, employing manufactured delivery systems as the delivery systems; oral liquids and topical creams are featured.
  • Discuss the importance of implementing a set of rules to ensure dosing accuracy, precision, and repeatability.
  • Review preparatory procedures for variable compositions, i.e., solutions and dispersions (suspensions and emulsions).
  • Assess active pharmaceutical ingredient characteristics and their impact in the mix.
  • Address labelling and packaging requirements for compounded medications.
  • Identify handling and storage requirements for variable compounded medications.
  • Assign beyond-use dates for compounded medications in accordance with standards of practice.
  • Validate compounded medications for their required qualitative and quantitative parameters through internal and external testing.
  • Verify the accuracy, precision, and repeatability of three critical determinants of a compounded medication’s efficacy, reliability, and validity: the master formulation record’s detailing, the metered-dose dispensing technology, and human performance measures.
  • Manage the verification process for finished compounded preparations, ensuring identity, strength, and stability.